This page hosts real-time medical and academic literature searches on FASD and FAS. Check back frequently for the latest articles.
- Fetal/neonatal exposure to ethanol alters pulmonary immunity and increases the severity of respiratory infections17 February 2012, 10:34 am
In addition to the well-described developmental and neurological defects in children with fetal alcohol syndrome (FAS), lesions in immunity have also been reported. Several studies have documented fetal alcohol syndrome FAS children to have increased rates of bacterial infection not only during the newborn period, but well into the first decade. In order to model the effects of in utero alcohol exposure in the mouse, we utilized the ethanol-in-drinking water model. Specifically, female C57BL/6 m... - Housing in Environmental Complexity Following Wheel Running Augments Survival of Newly Generated Hippocampal Neurons in a Rat Model of Binge Alcohol Exposure During the Third Trimester Equivalent10 February 2012, 4:00 am
ConclusionsWR followed by EC could provide a behavioral model for developing interventions in humans to ameliorate hippocampal‐dependent impairments associated with fetal alcohol spectrum disorders. (Source: Alcoholism: Clinical and Experimental Research)... - Metabolic Biomarkers of Prenatal Alcohol Exposure in Human Embryonic Stem Cell-Derived Neural Lineages.10 February 2012, 4:00 am
CONCLUSIONS: EtOH exposure induces statistically significant changes to the metabolome profile of human embryoid bodies, neural progenitors, and neurons. Several of these metabolites are normally present in human serum, suggesting their usefulness as potential serum FASD biomarkers. These findings suggest the biochemical pathways that are affected by EtOH in the developing nervous system and delineate mechanisms of alcohol injury during human development. PMID: 22324771 [PubMed - as supplied... - Housing in Environmental Complexity Following Wheel Running Augments Survival of Newly Generated Hippocampal Neurons in a Rat Model of Binge Alcohol Exposure During the Third Trimester Equivalent.10 February 2012, 4:00 am
CONCLUSIONS: WR followed by EC could provide a behavioral model for developing interventions in humans to ameliorate hippocampal-dependent impairments associated with fetal alcohol spectrum disorders. PMID: 22324755 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)... - Pregnancy and Drinking among Women Offenders under Community Supervision in the United States: 2004–20086 February 2012, 6:36 pm
This study sets out to determine the prevalence, patterns, and correlates of alcohol consumption among women offenders on probation or parole in the United States. Analysis of data collected from seven waves of the National Survey on Drug Use and Health (2004–2008) were performed on women who were under community supervision during the year prior to the survey interview. Results revealed that 1.9% of women of child-bearing ages of 12–44 years in the general population were pregnant,... - Older Not Wiser: Risk of Prenatal Alcohol Use by Maternal Age3 February 2012, 4:51 pm
This study addresses this gap by examining potential risk factors associated with prenatal alcohol use (any versus none) by maternal age (<20, 20–25, 26–34, and 35 years or older). Descriptive and logistic regression analyses were completed on survey data from 9,004 pregnant women from the north central U.S. Descriptive statistics revealed teens in general had a higher level or greater occurrence of risk factors previously identified with prenatal drinking compared to older women... - Wonder Dog: A Golden Retriever Reaches a Raging Boy3 February 2012, 2:17 pm
A golden retriever was the only thing that could reach a raging, disconnected boy. (Source: NYT Health)... - Fetal Alcohol Spectrum Disorders--a Case-Control Study from India23 January 2012, 4:00 am
Conclusions: Children prenatally exposed to alcohol manifest several neurobehavioral problems compared to controls. Underlying malnutrition may have altered some of the clinical findings. (Source: Journal of Tropical Pediatrics)... - Neuroprotection with metformin and thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons19 January 2012, 4:00 am
Conclusion: These findings suggested that Met and TQ are strong protective agents against ethanol-induced neuronal apoptosis in primary rat cortical neurons. The collective data demonstrated that Met and TQ have the potential to ameliorate ethanol neurotoxicity and revealed a possible protective target mechanism for the damaging effects of ethanol during early brain development. (Source: BMC Neuroscience - Latest articles)... - No Safe Level Of Alcohol During Pregnancy18 January 2012, 9:00 am
The authors of a study published online on Tuesday that was designed to overcome the difficulties of obtaining accurate and reliable data in Fetal Alcohol Syndrome research, say their findings reinforce the warning that there is no safe level of alcohol consumption during pregnancy. The lead author of the study is Haruna Sawada Feldman, a post-doctoral student in the University of California, San Diego pediatrics department, where senior author Christina Chambers, is a professor. The study is pu... - The Damage Of Alcohol By Timing And Exposure During Pregnancy Quantified By Researchers18 January 2012, 7:00 am
Prenatal exposure to alcohol is associated with a spectrum of abnormalities, referred to as Fetal Alcohol Spectrum Disorders. Physical features of the more serious Fetal Alcohol Syndrome (FAS) include smooth philtrum, thin vermillion border, short palpebral fissures, microcephaly, and growth deficiencies in weight and height. A new study has specified how specific quantities of alcohol exposure, patterns of drinking, and timing of exposure can have an impact on each of these features... (Source:... - No safe time to drink while pregnant18 January 2012, 4:05 am
SAN DIEGO, Jan. 17 (UPI) -- U.S. researchers say they have found new links between the timing of alcohol consumption during pregnancy and certain characteristics of fetal alcohol syndrome. (Source: Health News - UPI.com)... - Study: No alcohol intake safe during pregnancy17 January 2012, 4:29 pm
A new study pinpoints the latter half of the first trimester as a critical time in the development of fetal alcohol syndrome. (Source: USATODAY.com Health)... - No Alcohol Intake Safe in Pregnancy (CME/CE)17 January 2012, 1:00 pm
(MedPage Today) -- Any alcohol consumption during pregnancy puts the newborn at risk for fetal alcohol syndrome (FAS), results of a study showed. (Source: MedPage Today OB/GYN)... - Prenatal Alcohol Exposure Patterns and Alcohol-Related Birth Defects and Growth Deficiencies: A Prospective Study.17 January 2012, 4:00 am
Conclusions: Reduced birth length and weight, microcephaly, smooth philtrum, and thin vermillion border are associated with specific gestational timing of prenatal alcohol exposure and are dose-related without evidence of a threshold. Women should continue to be advised to abstain from alcohol consumption from conception throughout pregnancy. PMID: 22250768 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research)MedWorm Message: Please support the Docto...
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